HABP2

Across TCGA pan-cancer cohorts, HABP2 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated HABP2 data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HABP2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated HABP2 expression acts as an unfavorable survival marker, although some lineages such as GBM and CCRCC show a favorable association.

COAD, UCEC, and GBM are the cancer types where HABP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.869	1.000	.011	54	view →
UCEC	DFS	Median	III,IV	0.424	1.000	.003	16	view →
GBM	OS	Tertile	All	0.937	0.740	.003	15	view →
LSCC	DFS	Median	II,III,IV	0.836	1.000	.005	12	view →
CCRCC	DFS	Tertile	III,IV	0.841	0.436	.002	11	view →
PDAC	OS	Quartile	III,IV	0.362	1.000	.040	7	view →
LUAD	OS	Median	III,IV	0.242	0.674	.014	4	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

HABP2–COAD (DFS)

Open the COAD breakdown →