HABP2

Across TCGA patient cohorts, HABP2 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HABP2-associated genes across cancer lineages are ACC1, STAT3_pY705, and TFRC. Each is linked with HABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HABP2-to-partner and partner-to-HABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by HABP2-low versus HABP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HABP2→partner) and Y-score (partner→HABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.390	+1.920	.001	.008	3	2
UCEC	STAT3_pY705 →	-0.319	-1.678	<.001	.019	3	2
UCEC	TFRC →	+0.601	+2.263	<.001	<.001	3	2
UCEC	ASNS →	+0.429	+1.652	<.001	.006	3	2
UCEC	Cyclin-B1 →	+0.717	+3.115	<.001	<.001	3	2
UCEC	Di-Ras3 →	-0.180	-3.893	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

ACC1 by HABP2 expression — UCEC

Explore this box plot interactively →