H6PD

Across TCGA patient cohorts, H6PD RNA expression is significantly associated with the RNA expression of many other genes, with 19,888 significant associations in total. ACC shows the largest number of these associations.

The most reproducible H6PD-associated genes across cancer lineages are HP1BP3, UBE4B, and CDK13. Each is linked with H6PD in more than 33 cancer types. Because this analysis shows association rather than direction, both H6PD-to-partner and partner-to-H6PD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H6PD versus HP1BP3 in UVM, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H6PD→partner) and Y-score (partner→H6PD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	HP1BP3 →	+1.096	+0.744	<.001	<.001	3	34
ACC	UBE4B →	+1.702	+1.790	<.001	<.001	3	34
DLBC	CDK13 →	+1.028	+0.709	<.001	<.001	3	34
DLBC	CREBBP →	+1.152	+0.850	<.001	<.001	3	34
UVM	FBXO42 →	+0.759	+0.758	<.001	<.001	3	34
ACC	RGP1 →	+0.879	+0.996	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,888 associations by consensus.

H6PD vs HP1BP3 — UVM

Explore this scatter interactively →