H6PD

Across TCGA patient cohorts, H6PD RNA expression is significantly associated with the protein abundance of many other proteins, with 10,337 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H6PD-associated proteins across cancer lineages are RPL6, SRP68, and WDR19. Each is linked with H6PD in more than 4 cancer types. Because this analysis shows association rather than direction, both H6PD-to-partner and partner-to-H6PD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H6PD versus RPL6 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H6PD→partner) and Y-score (partner→H6PD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL6 →	-0.510	-0.484	<.001	.002	3	4
CCRCC	SRP68 →	-0.205	-0.436	.004	.007	2	5
BRCA	WDR19 →	+0.310	+0.417	<.001	.007	3	4
OV	ENO1 →	+0.400	+0.887	<.001	<.001	3	4
BRCA	TNS1_S1124 →	+1.023	+0.683	<.001	<.001	3	3
OV	TNS2_S102 →	+0.743	+0.671	.003	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,337 associations by consensus.

H6PD vs RPL6 — BRCA

Explore this scatter interactively →