H4C9

Across TCGA patient cohorts, H4C9 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H4C9-associated genes across cancer lineages are lymphatic Endothelial cells, mv Endothelial cells, and Basophils. Each is linked with H4C9 in more than 1 cancer types. Because this analysis shows association rather than direction, both H4C9-to-partner and partner-to-H4C9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by H4C9-low versus H4C9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C9→partner) and Y-score (partner→H4C9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.039	.019	2	1
UCEC	mv Endothelial cells →	-0.027	-2.448	.018	.020	2	1
UCEC	Basophils →	+0.181	+2.459	.027	.020	1	1
UCEC	Plasma cells →	-0.027	-2.416	.010	.021	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

lymphatic Endothelial cells by H4C9 expression — UCEC

Explore this box plot interactively →