H4C9

Across TCGA cell cohorts, H4C9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,738 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C9-associated GO terms across cancer lineages are Viral transcription, Spliceosomal complex assembly, and Protein localization to CENP-A containing chromatin. Each is linked with H4C9 in more than 10 cancer types. Because this analysis shows association rather than direction, both H4C9-to-partner and partner-to-H4C9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by H4C9-low versus H4C9-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C9→partner) and Y-score (partner→H4C9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Viral transcription →	+0.095	+0.524	<.001	<.001	3	9
OVARY	Spliceosomal complex assembly →	+0.092	+0.590	<.001	<.001	3	9
BREAST	Protein localization to CENP-A containing chromatin →	+0.346	+0.663	.007	<.001	1	11
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.157	+0.554	<.001	<.001	3	8
BLOOD_Leukemia	Positive regulation of hematopoietic progenitor cell differentiation →	+0.128	+0.500	<.001	<.001	3	8
OVARY	Regulation of proteasomal protein catabolic process →	+0.071	+0.737	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,738 associations by consensus.

Viral transcription by H4C9 expression — BREAST

Explore this box plot interactively →