H4C8

Across TCGA cell cohorts, H4C8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,304 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible H4C8-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Protein localization to CENP-A containing chromatin, and Very long-chain fatty acid catabolic process. Each is linked with H4C8 in more than 8 cancer types. Because this analysis shows association rather than direction, both H4C8-to-partner and partner-to-H4C8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor-mediated signaling pathway grouped by H4C8-low versus H4C8-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C8→partner) and Y-score (partner→H4C8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.077	+1.344	<.001	.002	3	8
CNS	Protein localization to CENP-A containing chromatin →	+0.308	+0.964	.005	<.001	1	9
OVARY	Very long-chain fatty acid catabolic process →	+0.098	+1.200	<.001	<.001	3	6
BLOOD_Lymphoma	Latent virus replication →	+0.124	+1.208	<.001	<.001	3	6
BLOOD_Lymphoma	Release from viral latency →	+0.124	+1.208	<.001	<.001	3	6
OVARY	Regulation of proteasomal protein catabolic process →	+0.055	+1.312	.004	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,304 associations by consensus.

Regulation of tumor necrosis factor-mediated signaling pathway by H4C8 expression — BLOOD_Lymphoma

Explore this box plot interactively →