H4C8

Across TCGA cell cohorts, H4C8 protein abundance is significantly associated with the RNA expression of many other genes, with 3,570 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C8-associated genes across cancer lineages are RAB15, SP4, and ZFHX3. Each is linked with H4C8 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C8-to-partner and partner-to-H4C8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H4C8 versus RAB15 in LUNG_SCLC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C8→partner) and Y-score (partner→H4C8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RAB15 →	+1.331	+0.841	.001	<.001	3	6
BONE	SP4 →	+1.354	+1.459	.001	.003	3	6
LUNG_SCLC	ZFHX3 →	+0.889	+0.760	<.001	<.001	3	5
LUNG_SCLC	WEE1 →	+0.795	+0.561	<.001	<.001	3	5
LUNG_SCLC	TINF2 →	+0.906	+0.716	.001	.003	3	5
BONE	PHLDB2 →	+2.687	+1.042	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

H4C8 vs RAB15 — LUNG_SCLC

Explore this scatter interactively →