H4C7

Across TCGA patient cohorts, H4C7 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H4C7-associated genes across cancer lineages are CD8+ T-cells and Class-switched memory B-cells. Each is linked with H4C7 in more than 1 cancer types. Because this analysis shows association rather than direction, both H4C7-to-partner and partner-to-H4C7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by H4C7-low versus H4C7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C7→partner) and Y-score (partner→H4C7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.014	+2.622	.030	.022	3	2
UCEC	Class-switched memory B-cells →	-0.063	-3.169	.045	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by H4C7 expression — UCEC

Explore this box plot interactively →