H4C5

Across TCGA patient cohorts, H4C5 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H4C5-associated proteins across cancer lineages are CTDSPL2, DLGAP5, and ECT2_T359. Each is linked with H4C5 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C5-to-partner and partner-to-H4C5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H4C5 versus CTDSPL2 in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C5→partner) and Y-score (partner→H4C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTDSPL2 →	+0.432	+0.704	<.001	<.001	3	6
LSCC	DLGAP5 →	+0.709	+0.780	<.001	<.001	3	4
OV	ECT2_T359 →	+1.262	+0.866	<.001	.003	3	4
OV	FUBP3 →	+0.265	+0.814	<.001	.004	3	4
LSCC	VRK1 →	+0.427	+0.674	<.001	<.001	3	4
HNSC	WIZ →	+0.377	+1.880	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,308 associations by consensus.

H4C5 vs CTDSPL2 — GBM

Explore this scatter interactively →