H4C5

Across TCGA patient cohorts, H4C5 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible H4C5-associated genes across cancer lineages are Astrocytes and MPP. Each is linked with H4C5 in more than 1 cancer types. Because this analysis shows association rather than direction, both H4C5-to-partner and partner-to-H4C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by H4C5-low versus H4C5-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C5→partner) and Y-score (partner→H4C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Astrocytes →	+0.078	+3.550	.049	.010	3	1
HNSC	MPP →	+0.020	+3.428	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Astrocytes by H4C5 expression — HNSC

Explore this box plot interactively →