H4C5

Across TCGA cell cohorts, H4C5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,983 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C5-associated GO terms across cancer lineages are Viral transcription, Regulation of RNA splicing, and Regulation of mRNA processing. Each is linked with H4C5 in more than 11 cancer types. Because this analysis shows association rather than direction, both H4C5-to-partner and partner-to-H4C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by H4C5-low versus H4C5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C5→partner) and Y-score (partner→H4C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Viral transcription →	+0.110	+0.546	.002	.006	3	12
OVARY	Regulation of RNA splicing →	+0.077	+0.805	<.001	<.001	3	10
OVARY	Regulation of mRNA processing →	+0.088	+0.924	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.092	+0.602	<.001	.007	3	8
SOFT_TISSUE	Microtubule organizing center organization →	+0.065	+0.549	.001	.001	3	8
PANCREAS	Regulation of DNA-templated transcription initiation →	+0.054	+1.079	.005	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,983 associations by consensus.

Viral transcription by H4C5 expression — LUNG_SCLC

Explore this box plot interactively →