Across TCGA patient cohorts, H4C3 RNA expression is significantly associated with the RNA expression of many other genes, with 15,007 significant associations in total. THYM shows the largest number of these associations.

The most reproducible H4C3-associated genes across cancer lineages are H2BC17, H4C5, and H4C4. Each is linked with H4C3 in more than 29 cancer types. Because this analysis shows association rather than direction, both H4C3-to-partner and partner-to-H4C3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C3→partner) and Y-score (partner→H4C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	H2BC17 →	+1.511	+1.101	<.001	<.001	3	29
SCLC	H4C5 →	+1.379	+0.931	<.001	<.001	3	29
TGCT	H4C4 →	+1.461	+0.857	<.001	<.001	3	29
CHOL	H2AC17 →	+1.232	+0.691	<.001	<.001	2	30
DLBC	H1-4 →	+1.557	+1.342	<.001	<.001	3	29
TGCT	H2AC16 →	+1.742	+0.926	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,007 associations by consensus.

Exploration

H4C3 survival (RNA) · tumor vs normal (RNA) · all H4C3 data types