H4C2

Across TCGA patient cohorts, H4C2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,898 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H4C2-associated proteins across cancer lineages are PRC1, ZWILCH, and RFC5. Each is linked with H4C2 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C2-to-partner and partner-to-H4C2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H4C2 versus PRC1 in LUAD, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C2→partner) and Y-score (partner→H4C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRC1 →	+0.656	+0.670	<.001	<.001	3	6
LUAD	ZWILCH →	+0.538	+0.579	<.001	<.001	3	6
LSCC	RFC5 →	+0.411	+0.653	<.001	<.001	3	6
LUAD	RRM2 →	+0.803	+0.660	<.001	<.001	3	6
GBM	SMC2 →	+0.686	+0.944	<.001	<.001	3	6
LUAD	WDHD1 →	+0.735	+0.688	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,898 associations by consensus.

H4C2 vs PRC1 — LUAD

Explore this scatter interactively →