H4C15

Across TCGA patient cohorts, H4C15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,302 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H4C15-associated GO terms across cancer lineages are Innate immune response in mucosa, Regulation of cytokinesis, and Mitochondrial DNA replication. Each is linked with H4C15 in more than 10 cancer types. Because this analysis shows association rather than direction, both H4C15-to-partner and partner-to-H4C15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Innate immune response in mucosa grouped by H4C15-low versus H4C15-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C15→partner) and Y-score (partner→H4C15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Innate immune response in mucosa →	+0.058	+0.098	<.001	<.001	3	11
ESCA	Regulation of cytokinesis →	+0.051	+0.105	.005	.001	3	10
ESCA	Mitochondrial DNA replication →	+0.067	+0.125	<.001	.002	2	10
ESCA	Protein monoubiquitination →	+0.049	+0.128	.002	<.001	3	9
ESCA	Protein localization to CENP-A containing chromatin →	+0.057	+0.128	<.001	<.001	3	8
ESCA	Base-excision repair →	+0.060	+0.126	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,302 associations by consensus.

Innate immune response in mucosa by H4C15 expression — STAD

Explore this box plot interactively →