Across TCGA patient cohorts, H4C11 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,049 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H4C11-associated proteins across cancer lineages are RFC2, RRM2, and WDHD1_S407. Each is linked with H4C11 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C11-to-partner and partner-to-H4C11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C11→partner) and Y-score (partner→H4C11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.409	+0.624	<.001	<.001	3	6
LUAD	RRM2 →	+0.636	+0.538	<.001	<.001	3	6
GBM	WDHD1_S407 →	+0.862	+0.999	<.001	<.001	3	6
LSCC	MCM3 →	+0.677	+0.633	<.001	<.001	3	6
LSCC	MCM5 →	+0.639	+0.627	<.001	<.001	3	6
LUAD	RFC1_T506 →	+0.922	+0.613	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,049 associations by consensus.

Exploration

H4C11 survival (RNA) · tumor vs normal (RNA) · all H4C11 data types