Across TCGA patient cohorts, H4C11 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible H4C11-associated genes across cancer lineages are RN7SL632P, RNA5SP168, and LINC02676. Each is linked with H4C11 in more than 1 cancer types. Because this analysis shows association rather than direction, both H4C11-to-partner and partner-to-H4C11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C11→partner) and Y-score (partner→H4C11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL632P →	+0.179	+4.826	<.001	.001	3	2
UCEC	RNA5SP168 →	+0.777	+5.621	.001	.004	3	2
LUSC	LINC02676 →	+0.257	+5.151	<.001	.007	3	2
HNSC	FXYD6P3 →	+0.099	+4.754	<.001	.005	3	1
HNSC	RNU6-1324P →	+0.227	+4.424	<.001	.008	3	1
HNSC	MIR130A →	+0.351	+4.498	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

H4C11 survival (RNA) · tumor vs normal (RNA) · all H4C11 data types