Across TCGA cell cohorts, H4-16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,777 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4-16-associated GO terms across cancer lineages are Viral transcription, Late viral transcription, and Regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with H4-16 in more than 15 cancer types. Because this analysis shows association rather than direction, both H4-16-to-partner and partner-to-H4-16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4-16→partner) and Y-score (partner→H4-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral transcription →	+0.116	+1.147	.005	.002	3	16
BONE	Late viral transcription →	+0.131	+1.277	.003	<.001	3	14
OESOPHAGUS	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.082	+0.957	<.001	.001	3	13
OESOPHAGUS	Negative regulation of autophagy →	+0.054	+0.978	.008	<.001	3	12
OESOPHAGUS	Regulation of mRNA splicing, via spliceosome →	+0.105	+1.684	.001	<.001	3	12
STOMACH	Cytosolic transport →	+0.052	+0.885	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,777 associations by consensus.

Exploration

H4-16 survival (RNA) · tumor vs normal (RNA) · all H4-16 data types