H3P7

Across TCGA pan-cancer cohorts, H3P7 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated H3P7 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher H3P7 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated H3P7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and COAD show a favorable association.

HNSC, LIHC, and MESO are the cancer types where H3P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.827	0.457	.001	72	view →
LIHC	DFS	Tertile	All	0.409	0.590	.003	72	view →
MESO	OS	Tertile	III,IV	0.178	0.676	.001	43	view →
THCA	OS	Quartile	III,IV	0.845	0.968	.002	32	view →
UCEC	DFS	Tertile	All	0.581	0.673	.021	30	view →
LUSC	DFS	Quartile	III,IV	0.225	0.818	.002	24	view →
COAD	OS	Tertile	All	0.955	0.836	.014	23	view →
UVM	OS	Tertile	III,IV	0.268	0.693	.025	18	view →
PAAD	OS	Quartile	All	0.641	0.311	.002	15	view →
ESCA	DFS	Median	II,III,IV	0.606	0.428	.007	14	view →
KICH	DFS	Tertile	All	0.514	0.951	.001	12	view →
STAD	DFS	Median	IV	0.134	0.500	.005	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

H3P7–HNSC (DFS)

Open the HNSC breakdown →