H3P6

Across TCGA patient cohorts, H3P6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,690 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H3P6-associated proteins across cancer lineages are RPRD2, BROX, and SDE2. Each is linked with H3P6 in more than 4 cancer types. Because this analysis shows association rather than direction, both H3P6-to-partner and partner-to-H3P6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3P6 versus RPRD2 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P6→partner) and Y-score (partner→H3P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD2 →	+0.305	+0.619	<.001	<.001	3	5
LSCC	BROX →	+0.450	+0.807	<.001	<.001	3	5
GBM	SDE2 →	+0.225	+0.813	.001	<.001	3	4
GBM	KDM1A →	+0.369	+0.871	.001	.001	3	4
GBM	ARID4B →	+0.255	+0.873	.003	<.001	3	4
OV	BRD7 →	+0.391	+0.907	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,690 associations by consensus.

H3P6 vs RPRD2 — LSCC

Explore this scatter interactively →