H3P47

Across TCGA pan-cancer cohorts, H3P47 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated H3P47 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher H3P47 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H3P47 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

LIHC, ACC, and UCS are the cancer types where H3P47 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Quartile	All	0.651	0.852	.003	53	view →
ACC	OS	Quartile	All	0.628	0.931	.001	42	view →
UCS	OS	Median	IV	0.752	0.404	.013	30	view →
STAD	OS	Tertile	All	0.613	0.751	.006	30	view →
KIRP	OS	Tertile	All	0.530	0.855	<.001	25	view →
UVM	DFS	Tertile	III,IV	0.264	0.830	.031	21	view →
UCEC	DFS	Median	III,IV	0.858	0.731	.005	18	view →
ESCA	DFS	Median	All	0.318	0.469	.020	17	view →
THYM	DFS	Tertile	III,IV	0.481	1.000	.027	13	view →
PRAD	DFS	Quartile	All	0.942	0.839	.007	12	view →
MESO	OS	Tertile	All	0.175	0.571	.026	6	view →
PAAD	DFS	Quartile	II,III,IV	0.571	0.315	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

H3P47–LIHC (OS)

Open the LIHC breakdown →