Across TCGA patient cohorts, H3P45 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,356 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P45-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, Nucleotide-excision repair, and Obsolete regulation of dosage compensation by inactivation of X chromosome. Each is linked with H3P45 in more than 21 cancer types. Because this analysis shows association rather than direction, both H3P45-to-partner and partner-to-H3P45 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P45→partner) and Y-score (partner→H3P45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of telomere maintenance via telomere lengthening →	+0.049	+0.159	<.001	<.001	3	22
UCS	Nucleotide-excision repair →	+0.040	+0.083	<.001	.004	3	22
ESCA	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.070	+0.283	<.001	<.001	3	21
STAD	Protein-containing complex disassembly →	+0.043	+0.158	<.001	<.001	3	21
ESCA	Regulation of RNA splicing →	+0.051	+0.216	<.001	<.001	3	21
ESCA	Reticulophagy →	+0.049	+0.221	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,356 associations by consensus.

Exploration

H3P45 survival (RNA) · tumor vs normal (RNA) · all H3P45 data types