Across TCGA patient cohorts, H3P44 mutation is significantly associated with the RNA expression of many other genes, with 168 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H3P44-associated genes across cancer lineages are CDY7P, SLC16A12-AS1, and GEMIN2P1. Each is linked with H3P44 in more than 1 cancer types. Because this analysis shows association rather than direction, both H3P44-to-partner and partner-to-H3P44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P44→partner) and Y-score (partner→H3P44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CDY7P →	+0.031	+5.292	<.001	.006	3	2
SKCM	SLC16A12-AS1 →	+0.070	+6.469	<.001	.001	3	1
SKCM	GEMIN2P1 →	+0.064	+5.292	<.001	.006	3	1
SKCM	RPL5P16 →	+0.195	+5.436	<.001	.005	3	1
SKCM	LINC01100 →	+0.492	+5.362	<.001	.005	3	1
SKCM	HMGN1P9 →	+0.164	+5.680	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 168 associations by consensus.

Exploration

H3P44 survival (RNA) · tumor vs normal (RNA) · all H3P44 data types