H3P37

Across TCGA pan-cancer cohorts, H3P37 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of H3P37’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where H3P37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H3P37 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, BLCA, and THCA are the cancer types where H3P37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H3P37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.105	<.001	7	view →
BLCA	All	All	+0.088	.022	5	view →
THCA	All	All	−0.083	.002	2	view →
LUSC	Male	All	+0.076	.017	2	view →
LIHC	Male	All	+0.026	.015	2	view →
CHOL	All	All	+0.105	.023	1	view →
HNSC	All	All	+0.039	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

H3P37–KIRC

Open the KIRC breakdown →