H3P32

Across TCGA pan-cancer cohorts, H3P32 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated H3P32 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher H3P32 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated H3P32 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

CESC, LUSC, and LGG are the cancer types where H3P32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.668	0.834	.001	54	view →
LUSC	OS	Tertile	III,IV	0.284	0.675	.006	51	view →
LGG	DFS	Tertile	All	0.413	0.749	<.001	51	view →
BLCA	OS	Tertile	All	0.860	0.592	.013	39	view →
GBM	OS	Tertile	All	0.069	0.415	<.001	18	view →
PAAD	OS	Tertile	II,III,IV	1.000	0.405	.017	18	view →
SKCM	DFS	Tertile	II,III,IV	0.251	0.567	.019	18	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
DLBC	DFS	Tertile	All	0.492	0.854	.013	18	view →
OV	DFS	Tertile	All	0.442	0.364	.038	18	view →
BRCA	OS	Tertile	II,III,IV	0.482	0.572	.019	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

H3P32–CESC (DFS)

Open the CESC breakdown →