Across TCGA pan-cancer cohorts, H3P26 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated H3P26 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher H3P26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H3P26 expression acts as an unfavorable survival marker, although some lineages such as OV and CESC show a favorable association.

PAAD, OV, and UCEC are the cancer types where H3P26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.208	0.650	<.001	45	view →
OV	DFS	Tertile	II,III,IV	0.442	0.362	.030	36	view →
UCEC	DFS	Tertile	All	0.706	0.849	.003	36	view →
STAD	OS	Tertile	All	0.171	0.583	.012	33	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	27	view →
KIRC	OS	Tertile	II,III,IV	0.624	0.802	.007	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LUSC	DFS	Tertile	All	0.587	0.805	.003	18	view →
LUAD	DFS	Tertile	IV	0.374	0.748	.012	18	view →
LIHC	DFS	Tertile	II,III,IV	0.141	0.481	.004	18	view →
BLCA	DFS	Tertile	All	0.492	0.636	.037	9	view →
CESC	OS	Tertile	II,III,IV	0.906	0.449	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration

Same gene, other analysis: H3P26 tumor-vs-normal RNA expression · all H3P26 data types