H3P2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H3P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,466 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P2-associated GO terms across cancer lineages are JNK cascade, Viral genome replication, and RNA 3'-end processing. Each is linked with H3P2 in more than 14 cancer types. Because this analysis shows association rather than direction, both H3P2-to-partner and partner-to-H3P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK cascade grouped by H3P2-low versus H3P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P2→partner) and Y-score (partner→H3P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADJNK cascade →+0.046+0.271<.001<.001315
STADViral genome replication →+0.063+0.271<.001<.001314
STADRNA 3'-end processing →+0.063+0.302<.001<.001314
ESCARegulation of DNA-templated transcription elongation →+0.075+0.406.002<.001314
ESCAEndosome to lysosome transport →+0.068+0.414.001<.001314
STADAerobic respiration →+0.061+0.243<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,466 associations by consensus.

JNK cascade by H3P2 expression — STAD

Box plot of JNK cascade in H3P2-low vs H3P2-high samples in STAD.

Explore this box plot interactively →

Exploration