H3P17

Across TCGA patient cohorts, H3P17 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,005 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H3P17-associated GO terms across cancer lineages are Positive regulation of intrinsic apoptotic signaling pathway, Water-soluble vitamin metabolic process, and Regulation of synapse structure or activity. Each is linked with H3P17 in more than 5 cancer types. Because this analysis shows association rather than direction, both H3P17-to-partner and partner-to-H3P17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intrinsic apoptotic signaling pathway grouped by H3P17-low versus H3P17-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P17→partner) and Y-score (partner→H3P17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of intrinsic apoptotic signaling pathway →	+0.243	+0.032	<.001	.001	3	5
STAD	Water-soluble vitamin metabolic process →	+0.177	+0.035	<.001	<.001	3	5
STAD	Regulation of synapse structure or activity →	+0.108	+0.034	<.001	.001	3	5
STAD	Regulated exocytosis →	+0.106	+0.062	<.001	<.001	2	6
STAD	Sterol transport →	+0.132	+0.053	<.001	.003	3	4
ESCA	Regulation of exocytosis →	+0.207	+0.072	<.001	.009	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,005 associations by consensus.

Positive regulation of intrinsic apoptotic signaling pathway by H3P17 expression — STAD

Explore this box plot interactively →