H3P13

Across TCGA pan-cancer cohorts, H3P13 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated H3P13 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher H3P13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated H3P13 expression acts as an unfavorable survival marker, although some lineages such as CESC and HNSC show a favorable association.

KIRC, KICH, and ACC are the cancer types where H3P13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.748	0.852	<.001	127	view →
KICH	OS	Quartile	All	0.542	0.938	<.001	56	view →
ACC	OS	Tertile	III,IV	0.555	0.980	.002	53	view →
CESC	OS	Median	All	0.863	0.735	.002	44	view →
HNSC	OS	Quartile	IV	0.618	0.319	<.001	40	view →
LUAD	DFS	Quartile	III,IV	0.657	0.189	.003	36	view →
LGG	DFS	Quartile	All	0.759	0.861	.006	19	view →
LIHC	OS	Quartile	III,IV	0.837	0.595	.018	19	view →
LAML	DFS	Quartile	All	0.215	0.584	.026	12	view →
SARC	OS	Median	All	0.763	0.875	.011	9	view →
TGCT	DFS	Tertile	All	0.879	0.698	.020	8	view →
UCEC	OS	Quartile	All	0.694	0.825	.013	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

H3P13–KIRC (DFS)

Open the KIRC breakdown →