Across TCGA pan-cancer cohorts, H3P10 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of H3P10’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where H3P10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H3P10 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUAD and KIRC are the cancer types where H3P10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H3P10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.202	.011	2	view →
KIRC	Male	All	−0.023	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: H3P10 RNA expression & survival · all H3P10 data types