H3C6

Across TCGA patient cohorts, H3C6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,120 significant associations in total. THCA shows the largest number of these associations.

The most reproducible H3C6-associated GO terms across cancer lineages are Nuclear-transcribed mRNA poly(A) tail shortening, Stress granule assembly, and Obsolete ncRNA catabolic process. Each is linked with H3C6 in more than 24 cancer types. Because this analysis shows association rather than direction, both H3C6-to-partner and partner-to-H3C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA poly(A) tail shortening grouped by H3C6-low versus H3C6-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C6→partner) and Y-score (partner→H3C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.054	+0.972	.002	<.001	3	24
DLBC	Stress granule assembly →	+0.083	+1.305	<.001	<.001	3	24
DLBC	Obsolete ncRNA catabolic process →	+0.048	+0.755	.001	.001	2	25
DLBC	TORC1 signaling →	+0.056	+1.091	.009	<.001	2	25
DLBC	Positive regulation of cytoplasmic translational initiation →	+0.078	+1.120	<.001	<.001	3	24
DLBC	Vesicle targeting →	+0.053	+0.966	.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,120 associations by consensus.

Nuclear-transcribed mRNA poly(A) tail shortening by H3C6 expression — DLBC

Explore this box plot interactively →