H3C4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H3C4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible H3C4-associated genes across cancer lineages are CD4+ Tem and CD4+ Tcm. Each is linked with H3C4 in more than 1 cancer types. Because this analysis shows association rather than direction, both H3C4-to-partner and partner-to-H3C4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C4→partner) and Y-score (partner→H3C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD4+ Tem →+0.010+5.623<.001.00131
HNSCCD4+ Tcm →+0.010+4.468<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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