H3C3

Across TCGA patient cohorts, H3C3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H3C3-associated proteins across cancer lineages are MKI67_S357, NCAPD2, and NRDC. Each is linked with H3C3 in more than 5 cancer types. Because this analysis shows association rather than direction, both H3C3-to-partner and partner-to-H3C3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3C3 versus MKI67_S357 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C3→partner) and Y-score (partner→H3C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MKI67_S357 →	+1.750	+1.450	<.001	<.001	3	6
GBM	NCAPD2 →	+0.719	+1.555	<.001	<.001	3	6
GBM	NRDC →	+0.352	+1.582	<.001	<.001	3	6
LUAD	MKI67 →	+0.875	+1.264	<.001	<.001	3	5
LUAD	MKI67_S2528 →	+1.776	+1.645	<.001	<.001	3	5
LUAD	MKI67_S2828 →	+1.131	+1.355	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,550 associations by consensus.

H3C3 vs MKI67_S357 — LUAD

Explore this scatter interactively →