Across TCGA patient cohorts, H3C15 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,405 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible H3C15-associated proteins across cancer lineages are PRC1_T481, GINS4, and TRIM33_S862. Each is linked with H3C15 in more than 4 cancer types. Because this analysis shows association rather than direction, both H3C15-to-partner and partner-to-H3C15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C15→partner) and Y-score (partner→H3C15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRC1_T481 →	+0.911	+0.168	<.001	.003	3	5
LSCC	GINS4 →	+0.705	+0.176	<.001	.001	3	5
LSCC	TRIM33_S862 →	+0.526	+0.185	<.001	.001	3	4
UCEC	UBTF_S484 →	+0.954	+0.451	<.001	.003	3	4
LUAD	ZNF622_S143 →	+0.877	+0.268	<.001	.009	3	4
LUAD	MKI67_S2528 →	+1.214	+0.145	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,405 associations by consensus.

Exploration

H3C15 survival (RNA) · tumor vs normal (RNA) · all H3C15 data types