Across TCGA cell cohorts, H3C15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H3C15-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, RNA catabolic process, and Nucleic acid catabolic process. Each is linked with H3C15 in more than 13 cancer types. Because this analysis shows association rather than direction, both H3C15-to-partner and partner-to-H3C15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C15→partner) and Y-score (partner→H3C15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of mRNA splicing, via spliceosome →	+0.065	+1.002	.002	.003	3	14
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.047	+0.665	.004	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.045	+0.677	.002	.003	3	11
BLOOD_Myeloma	Regulation of protein sumoylation →	+0.090	+1.207	<.001	.001	3	10
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.152	+0.558	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.086	+0.760	.003	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,615 associations by consensus.

Exploration

H3C15 survival (RNA) · tumor vs normal (RNA) · all H3C15 data types