Across TCGA cell cohorts, H3C12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,626 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H3C12-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Interstrand cross-link repair, and DNA recombination. Each is linked with H3C12 in more than 7 cancer types. Because this analysis shows association rather than direction, both H3C12-to-partner and partner-to-H3C12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C12→partner) and Y-score (partner→H3C12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mRNA 3'-end processing →	+0.109	+0.329	<.001	.001	3	8
BREAST	Interstrand cross-link repair →	+0.073	+0.738	<.001	<.001	3	8
SOFT_TISSUE	DNA recombination →	+0.059	+0.314	<.001	<.001	3	8
BLOOD_Leukemia	DNA-templated transcription initiation →	+0.029	+0.330	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Positive regulation of retrograde protein transport, ER to cytosol →	-0.078	-0.313	<.001	.004	3	7
LUNG_NSCLC_LUSC	Negative regulation of cell cycle phase transition →	+0.052	+0.588	.006	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,626 associations by consensus.

Exploration

H3C12 survival (RNA) · tumor vs normal (RNA) · all H3C12 data types