H3C10

Across TCGA cell cohorts, H3C10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,481 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible H3C10-associated GO terms across cancer lineages are Regulation of proteasomal protein catabolic process, Autophagosome organization, and Vacuole organization. Each is linked with H3C10 in more than 7 cancer types. Because this analysis shows association rather than direction, both H3C10-to-partner and partner-to-H3C10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal protein catabolic process grouped by H3C10-low versus H3C10-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C10→partner) and Y-score (partner→H3C10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of proteasomal protein catabolic process →	+0.061	+1.208	.001	<.001	3	8
OVARY	Autophagosome organization →	+0.046	+0.914	<.001	.002	3	8
OVARY	Vacuole organization →	+0.046	+1.288	<.001	<.001	3	8
BLOOD_Leukemia	Protein localization to CENP-A containing chromatin →	+0.223	+1.255	.004	<.001	3	7
OVARY	Process utilizing autophagic mechanism →	+0.046	+1.074	<.001	.001	3	7
OVARY	Autophagy →	+0.046	+1.074	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,481 associations by consensus.

Regulation of proteasomal protein catabolic process by H3C10 expression — OVARY

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