H3C1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H3C1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible H3C1-associated genes across cancer lineages are Fibroblasts. Each is linked with H3C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both H3C1-to-partner and partner-to-H3C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by H3C1-low versus H3C1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C1→partner) and Y-score (partner→H3C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMFibroblasts →+0.022+5.797<.001.03531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Fibroblasts by H3C1 expression — SKCM

Box plot of Fibroblasts in H3C1-low vs H3C1-high samples in SKCM.

Explore this box plot interactively →

Exploration