H2BP5

Across TCGA patient cohorts, H2BP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,551 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H2BP5-associated GO terms across cancer lineages are Regulation of protein polymerization, Activation of cysteine-type endopeptidase activity involved in apoptotic process, and Mitotic spindle assembly. Each is linked with H2BP5 in more than 4 cancer types. Because this analysis shows association rather than direction, both H2BP5-to-partner and partner-to-H2BP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein polymerization grouped by H2BP5-low versus H2BP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BP5→partner) and Y-score (partner→H2BP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein polymerization →	+0.222	+0.040	<.001	<.001	3	5
STAD	Activation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.221	+0.028	<.001	<.001	3	5
STAD	Mitotic spindle assembly →	+0.252	+0.063	<.001	<.001	3	4
STAD	Positive regulation of intracellular protein transport →	+0.263	+0.051	<.001	.001	3	4
STAD	Cellular senescence →	+0.227	+0.052	<.001	.001	3	4
STAD	Activation of GTPase activity →	+0.179	+0.039	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,551 associations by consensus.

Regulation of protein polymerization by H2BP5 expression — STAD

Explore this box plot interactively →