H2BP3

Across TCGA patient cohorts, H2BP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,275 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H2BP3-associated GO terms across cancer lineages are Protein localization to CENP-A containing chromatin, tRNA metabolic process, and RNA modification. Each is linked with H2BP3 in more than 14 cancer types. Because this analysis shows association rather than direction, both H2BP3-to-partner and partner-to-H2BP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to CENP-A containing chromatin grouped by H2BP3-low versus H2BP3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BP3→partner) and Y-score (partner→H2BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein localization to CENP-A containing chromatin →	+0.069	+0.293	<.001	<.001	3	15
STAD	tRNA metabolic process →	+0.045	+0.193	<.001	<.001	3	12
STAD	RNA modification →	+0.041	+0.190	<.001	<.001	3	12
TGCT	Negative regulation of megakaryocyte differentiation →	+0.047	+0.152	<.001	<.001	2	12
ESCA	Protein localization to chromosome, centromeric region →	+0.056	+0.290	.002	.001	3	11
ESCA	mRNA 3'-end processing →	+0.063	+0.344	.004	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,275 associations by consensus.

Protein localization to CENP-A containing chromatin by H2BP3 expression — ESCA

Explore this box plot interactively →