H2BP2

Across TCGA pan-cancer cohorts, H2BP2 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated H2BP2 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher H2BP2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2BP2 expression acts as an unfavorable survival marker.

OV are the cancer types where H2BP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	IV	0.007	0.760	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

H2BP2–OV (OS)

Open the OV breakdown →