H2BC7

Across TCGA pan-cancer cohorts, H2BC7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated H2BC7 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher H2BC7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2BC7 expression acts as an unfavorable survival marker.

UCEC and BLCA are the cancer types where H2BC7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.066	0.755	<.001	12	view →
BLCA	OS	Median	III,IV	0.117	0.684	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

H2BC7–UCEC (OS)

Open the UCEC breakdown →