H2BC5

Across TCGA patient cohorts, H2BC5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible H2BC5-associated genes across cancer lineages are NKT, MPP, and cDC. Each is linked with H2BC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC5-to-partner and partner-to-H2BC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKT grouped by H2BC5-low versus H2BC5-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC5→partner) and Y-score (partner→H2BC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NKT →	-0.102	-2.991	.016	.036	2	2
LUAD	MPP →	+0.021	+5.995	<.001	<.001	3	1
HNSC	cDC →	-0.088	-3.000	.040	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

NKT by H2BC5 expression — HNSC

Explore this box plot interactively →