H2BC5

Across TCGA cell cohorts, H2BC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,079 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H2BC5-associated GO terms across cancer lineages are Negative regulation of transcription elongation by RNA polymerase II, Regulation of proteasomal protein catabolic process, and Autophagosome organization. Each is linked with H2BC5 in more than 8 cancer types. Because this analysis shows association rather than direction, both H2BC5-to-partner and partner-to-H2BC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription elongation by RNA polymerase II grouped by H2BC5-low versus H2BC5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC5→partner) and Y-score (partner→H2BC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of transcription elongation by RNA polymerase II →	+0.095	+1.918	.007	.002	3	9
OVARY	Regulation of proteasomal protein catabolic process →	+0.057	+1.816	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Autophagosome organization →	+0.043	+1.143	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Autophagy of mitochondrion →	+0.054	+1.158	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Autophagosome assembly →	+0.044	+1.121	<.001	<.001	3	9
KIDNEY	Establishment of protein localization to membrane →	+0.068	+1.613	.003	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,079 associations by consensus.

Negative regulation of transcription elongation by RNA polymerase II by H2BC5 expression — STOMACH

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