H2BC5

Across TCGA cell cohorts, H2BC5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible H2BC5-associated genes across cancer lineages are CHIA, OPRPN, and OR2A2. Each is linked with H2BC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC5-to-partner and partner-to-H2BC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHIA grouped by H2BC5-low versus H2BC5-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC5→partner) and Y-score (partner→H2BC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CHIA →	+1.107	+4.087	.002	.009	3	1
URINARY_TRACT	OPRPN →	+0.045	+4.087	<.001	.009	3	1
URINARY_TRACT	OR2A2 →	+0.035	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CHIA by H2BC5 expression — URINARY_TRACT

Explore this box plot interactively →