H2BC20P

Across TCGA pan-cancer cohorts, H2BC20P RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of H2BC20P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where H2BC20P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2BC20P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, HNSC, and BLCA are the cancer types where H2BC20P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2BC20P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+1.110	<.001	11	view →
HNSC	All	IV	+0.887	<.001	11	view →
BLCA	All	All	+1.200	<.001	10	view →
COAD	Male	II,III,IV	+0.877	<.001	10	view →
LIHC	Female	II,III,IV	+1.491	<.001	9	view →
LUAD	Male	All	+1.347	<.001	9	view →
READ	All	All	+0.943	.002	7	view →
BRCA	All	III,IV	+1.838	<.001	6	view →
LUSC	Female	All	+1.402	<.001	6	view →
CHOL	Male	All	+3.105	<.001	5	view →
KIRP	All	II,III,IV	+0.688	.004	5	view →
KICH	All	All	−0.594	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

H2BC20P–KIRC

Open the KIRC breakdown →