H2BC14

Across TCGA patient cohorts, H2BC14 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,388 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible H2BC14-associated proteins across cancer lineages are LIG1_S76, POLD3, and NCL_T121. Each is linked with H2BC14 in more than 6 cancer types. Because this analysis shows association rather than direction, both H2BC14-to-partner and partner-to-H2BC14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2BC14 versus LIG1_S76 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC14→partner) and Y-score (partner→H2BC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LIG1_S76 →	+0.880	+1.868	<.001	<.001	3	7
LSCC	POLD3 →	+0.446	+1.341	.002	<.001	3	7
LUAD	NCL_T121 →	+1.395	+1.000	<.001	<.001	3	6
GBM	RRM2 →	+0.744	+1.274	<.001	.002	3	6
LUAD	RRP36_S73 →	+0.825	+1.081	<.001	<.001	3	6
LUAD	CDK1 →	+0.664	+1.042	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,388 associations by consensus.

H2BC14 vs LIG1_S76 — GBM

Explore this scatter interactively →