H2BC14

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H2BC14 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2BC14-associated genes across cancer lineages are HSC and DC. Each is linked with H2BC14 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC14-to-partner and partner-to-H2BC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSC grouped by H2BC14-low versus H2BC14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC14→partner) and Y-score (partner→H2BC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHSC →+0.132+2.815.016.03631
READDC →+0.023+3.231.034.04431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

HSC by H2BC14 expression — UCEC

Box plot of HSC in H2BC14-low vs H2BC14-high samples in UCEC.

Explore this box plot interactively →

Exploration