Across TCGA pan-cancer cohorts, H2BC13 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated H2BC13 data layer compared with 22 for mass-spec protein.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher H2BC13 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2BC13 expression acts as an unfavorable survival marker.
KIRP, OV, and DLBC are the cancer types where H2BC13 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.