Across TCGA pan-cancer cohorts, H2BC12 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated H2BC12 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher H2BC12 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2BC12 expression acts as an unfavorable survival marker.

LIHC are the cancer types where H2BC12 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.017	0.784	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: H2BC12 tumor-vs-normal RNA expression · all H2BC12 data types